KEGG   Bos taurus (cow): 527411
Entry
527411            CDS       T01008                                 
Symbol
TOP3A
Name
(RefSeq) DNA topoisomerase 3-alpha
  KO
K03165  DNA topoisomerase III [EC:5.6.2.1]
Organism
bta  Bos taurus (cow)
Pathway
bta03440  Homologous recombination
bta03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:bta00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    527411 (TOP3A)
   03460 Fanconi anemia pathway
    527411 (TOP3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:bta03032]
    527411 (TOP3A)
   03400 DNA repair and recombination proteins [BR:bta03400]
    527411 (TOP3A)
Enzymes [BR:bta01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     527411 (TOP3A)
DNA replication proteins [BR:bta03032]
 Eukaryotic type
  DNA Topoisomerases
   527411 (TOP3A)
DNA repair and recombination proteins [BR:bta03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Bloom's syndrome complex (BTR)
     527411 (TOP3A)
   FA (Fanconi anemia) pathway
     527411 (TOP3A)
SSDB
Motif
Pfam: Topoisom_bac zf-GRF Toprim zf-C4_Topoisom zf-C2H2_10
Other DBs
NCBI-GeneID: 527411
NCBI-ProteinID: NP_001071443
BGD-bta: BT29310
Ensembl: ENSBTAG00000017087
VGNC: 49584
UniProt: A0JN73
Position
19:34359100..34380723
AA seq 1002 aa
MIFPAAHRALRGLPRPGTRALTRAAMEVALRGVRKILCVAEKNDAAKGIADLLSGGRMRR
REGLSRFNKIYEFDYHLCGQNVTMVMTSVSGHLLAHDFRMQFRKWQSCNPLVLFEAEIEK
YCPENFVDIKKTLEREAQQCQALVIWTDCDREGENIGFEVIHVCKAVKPSLQVLRARFSE
ITTRAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQKIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEVFHKIRVTHDHRDGVVEFSWKRHRLFNHTACLVLY
QMCMEDPRAMVVEVRSKAKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLDLAALVEQQTPDPRWGAFARNILERGGPTPRNGNKSDQAHPPIHPT
KYTDSLQGDEQRLYELIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV
YPYDRWSDKTLPVYEQGTCFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKLVVLHQQVQKYKQVFIEAVAKARKLDEALSQYFGAATEVAPQDALPAVPEPIRKCPQC
SRDMVLKTRKSGGFYLGCTGFPECRSAVWFPDSVLEASRDVSVCPVCQPHPVYRLKFKFK
RGSLPPTMPLEFVGCIGGCDETLREILALRFSQGAARVSQPASQTSGYLQASQSLNRMDS
GQQGQPRPPVTRPSKALTRTLPPPAVESESNSVTCNCGQEALLLTVRKEGPNQGRQFYKC
GSGGCSFFLWADSGHPGAGPPSSASRPPGGPLEHPPGSGTLLGGSSRPGSGGSGGASCLC
GQPAVTRTVQKEGPNQGRQFHTCAQPREHQCGFFQWVDENVAPGTFGGPLWPGSRRGTQG
LEARSKRPRAGSSDTGSATKKPRKCSLCHQPGHTRPFCPQNR
NT seq 3009 nt   +upstreamnt  +downstreamnt
atgatatttccggccgcccaccgcgctctccgggggctgccgcggcccggtactcgggcc
ctgactcgcgccgccatggaggtggccctgcgaggcgtgcggaaaatcctttgcgtggcc
gagaagaacgacgcggccaagggcatagccgacttgctgtctggcggccgcatgcggcgg
agggaaggactttcaagattcaacaagatctatgagtttgattatcatctgtgtggccag
aatgtcaccatggtaatgacctcagtctcaggacacttgctggcccatgatttccggatg
cagtttcgcaaatggcagagctgcaatcctcttgtcctgtttgaagcagaaattgaaaag
tactgcccagagaattttgtagacatcaagaaaactctggagcgagaggcccagcaatgc
caggccctggtgatttggaccgactgcgacagagagggtgaaaacattgggtttgaggtc
atccacgtgtgcaaggccgtgaagcccagcctgcaggtgctgcgagcccgtttctccgag
atcaccacccgcgctgtccggacggcatgtgaaaaccttacggagcccgaccagagagtg
agcgatgccgtggatgtgaggcaggagttggacctgcggatcggggcggccttcaccagg
ttccagacgctgcggctgcagaagatcttccccgaggtgctggcagagcagcttatcagc
tacggcagctgccagttccccaccctggggttcgtggtggagaggttcaaagccattcag
gcatttgtgccagaagtcttccacaagatccgagtgactcatgaccacagggacggcgtg
gtagagttcagctggaaaaggcatcgtctcttcaatcacacggcatgtctcgtcctctac
cagatgtgcatggaggatcccagggcgatggtggtagaggtcaggtcaaaagccaagagc
aagtggaggcctcaggctctggacactgtggagctggagaagctggcatctcggaagttg
aggataaatgctaaagaaaccatgaggattgcagaaaagctctacacccaagggtacatc
agctatcctcgaactgaaacgaacattttccccaaagacctagacctggcggcactggtg
gagcaacagaccccggatccacgctggggggcctttgctcgaaacattctagagcgcggt
ggccccaccccacgcaatgggaataagtctgaccaagcgcaccctcccatccaccccacc
aaatacactgacagcctgcagggggatgagcagcgactgtacgagctcatcgtccgccac
ttcctggcctgctgctcgcaggatgcccagggccaggagaccactgtggagatcgacatc
gcgcaggagcgcttcgtggcccacggcctcatgatcctggcccggaactatctggacgtg
tacccgtatgatcgctggagtgacaagaccctccctgtctatgagcaaggcacctgcttt
cagcccagcactgtggagatggtggacggggagaccagtcccccccagctgctcaccgag
gctgacctcattgccctcatggagaagcacggcattggtacggacgccacgcacgctgag
cacatcgagaccatcaaggcccggatgtacgtcgggctcacgccagataagcgctttctc
cctgggcacctgggcatggggctcgtggaaggctatgactccatgggctacgagatgtcc
aagcctgatctgcgggccgagctggaggctgacctgaagctcatctgcgaggggaagaag
gacaagctggtggtcctgcatcagcaggtgcagaagtacaagcaggtgttcatcgaagcc
gtggccaaagccaggaagttggacgaggccttgtcccagtacttcggggcggctacagag
gtagccccacaggacgccctcccggctgtgcccgagcccatcaggaagtgtcctcagtgc
agccgggacatggttcttaagaccagaaagagtggcgggttttacctcggttgcacgggc
ttccctgagtgtcggtcggctgtctggttcccggacagcgtgctggaggccagcagggat
gtgagcgtgtgcccagtgtgccagccgcacccagtttacaggttgaagttcaagtttaaa
cgaggcagcctgcccccaaccatgcccctagaatttgtcggctgcatcggcgggtgtgat
gagaccctgagggagatcctggccctcaggttctcccagggcgctgcccgagtcagccag
cctgccagccagacctccggctacctgcaggctagccagtccctgaacagaatggacagt
ggccagcagggccagccccggccccccgtcaccaggccctcgaaggctttgaccaggact
cttcctccacccgccgttgagagtgagagcaactcggtgacctgcaactgtggccaggag
gccctgctgctcaccgtccggaaggagggccccaaccagggccgccagttctacaagtgt
ggcagtggtggctgcagcttctttctatgggctgacagcggccacccaggagccgggcct
ccctcctcagcgtccagacccccaggcggccccctggaacaccccccgggctcagggact
ctcttgggcgggtccagcaggcctggcagtggtggcagcggtggcgcatcctgcctgtgt
ggccagccggctgtcacgcgcaccgtgcagaaggaggggcccaaccagggccgccagttc
cacacgtgtgcccagccccgtgagcaccagtgcggcttcttccagtgggtggacgagaac
gtggccccagggaccttcggaggccccctctggccaggaagcaggagaggaacccagggg
ctggaggccagaagcaagaggcctcgggccggctcctcagacacagggtctgcaaccaag
aaaccccggaagtgcagcctttgccaccagcctggacatacccgtcccttctgtcctcag
aacagatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (32)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (59)   

Download RDF
DBGET integrated database retrieval system